A dynamic light scattering study on mutual diffusion coefficient of BSA in concentrated aqueous solutions
INFM, Dipartimento di Fisica dell'Università, I-06100 Perugia, Italy
Dipartimento di Scienze Ambientali, Sezione Chimica e Fisica, Università della Tuscia, I-01100, Viterbo, Italy
Accepted: 26 June 1998
Dynamic light scattering has been used to measure the mutual diffusion coefficient of bovine serum albumin under isothermal condition as a function of protein concentration and in the presence of a viscous cosolvent such as glycerol. The results are discussed in connection with the influence of the solvent envinronment on both direct and hydrodynamic interactions.
PACS: 87.15.Da – Physical chemistry of solutions of biomolecules; condensed states / 66.10.Cb – Diffusion and thermal diffusion
© EDP Sciences, 1998