Modeling molecular motors as folding-unfolding cycles
Niels Bohr Institute and NORDITA - Blegdamsvej 17, DK-2100 Ø, Denmark
Accepted: 27 January 2000
We propose a model for motor proteins based on a hierarchical Hamiltonian that we have previously introduced to describe protein folding. The proposed motor model has a power stroke of high efficiency and an overall dynamics that is consistent with a linear load-velocity response. The model suggests a connection between folding and function of allosteric proteins.
PACS: 87.15.He – Dynamics and conformal changes / 05.40.-a – Fluctuation phenomena, random processes, noise, and Brownian motion
© EDP Sciences, 2000