Dynamic light scattering as an investigating tool to study the global internal dynamics of a living cell nucleusM. Suissa1, C. Place1, 2, É. Goillot3, B. Berge1 and É. Freyssingeas1
1 Laboratoire de Physique, École Normale Supérieure de Lyon - 46 allée d'Italie, 69364 Lyon, France
2 Laboratoire transdisciplinaire Joliot-Curie, École Normale Supérieure de Lyon - 46 allée d'Italie, 69364 Lyon, France
3 Laboratoire de Biologie Moléculaire de la cellule, École Normale Supérieure de Lyon - 46 allée d'Italie, 69364 Lyon, France
received 6 December 2006; accepted in final form 21 March 2007; published May 2007
published online 20 April 2007
Recent progress in cellular biology has shown that the nucleus of a living cell is a structured integration of many functional domains with a complex spatial organization. This organization, as well as molecular and biochemical processes are time regulated. Despite a growing interest, the global internal dynamics of the nucleus is still unknown. In this letter, we show that this dynamics can be investigated successfully by means of dynamics light scattering experiments.
87.17.-d - Cellular structure and processes.
87.80.-y - Biological techniques and instrumentation; biomedical engineering.
78.35.+c - Brillouin and Rayleigh scattering; other light scattering.
© Europhysics Letters Association 2007