Issue
EPL
Volume 78, Number 3, May 2007
Article Number 38005
Number of page(s) 6
Section Interdisciplinary Physics and Related Areas of Science and Technology
DOI http://dx.doi.org/10.1209/0295-5075/78/38005
Published online 20 April 2007
EPL, 78 (2007) 38005
DOI: 10.1209/0295-5075/78/38005

Dynamic light scattering as an investigating tool to study the global internal dynamics of a living cell nucleus

M. Suissa1, C. Place1, 2, É. Goillot3, B. Berge1 and É. Freyssingeas1

1  Laboratoire de Physique, École Normale Supérieure de Lyon - 46 allée d'Italie, 69364 Lyon, France
2  Laboratoire transdisciplinaire Joliot-Curie, École Normale Supérieure de Lyon - 46 allée d'Italie, 69364 Lyon, France
3  Laboratoire de Biologie Moléculaire de la cellule, École Normale Supérieure de Lyon - 46 allée d'Italie, 69364 Lyon, France

eric.freyssingeas@ens-lyon.fr

received 6 December 2006; accepted in final form 21 March 2007; published May 2007
published online 20 April 2007

Abstract
Recent progress in cellular biology has shown that the nucleus of a living cell is a structured integration of many functional domains with a complex spatial organization. This organization, as well as molecular and biochemical processes are time regulated. Despite a growing interest, the global internal dynamics of the nucleus is still unknown. In this letter, we show that this dynamics can be investigated successfully by means of dynamics light scattering experiments.

PACS
87.17.-d - Cellular structure and processes.
87.80.-y - Biological techniques and instrumentation; biomedical engineering.
78.35.+c - Brillouin and Rayleigh scattering; other light scattering.

© Europhysics Letters Association 2007