A nonlinear cable-like model of amplified ionic wave propagation along microtubulesA. Priel1 and J. A. Tuszyński1, 2
1 Department of Physics, University of Alberta - Edmonton, Alberta, T6G 2J7, Canada
2 Experimental Oncology, Cross Cancer Institute - 11560 University Avenue, Edmonton, Alberta, T6G 1Z2, Canada
received 4 February 2008; accepted in final form 8 August 2008; published September 2008
published online 11 September 2008
The properties of ionic waves propagating along a microtubule in solution are analyzed in this paper. We derive the constitutive equations in the continuum limit, obtain appropriate parameter values from the tubulin structural data and solve numerically these equations finding their dependence on the range of parameter values. Possible biophysical implications of the results that may arise from the model are discussed.
87.15.Pc - Electronic and electrical properties.
87.16.Ln - Cytoskeleton.
87.15.ad - Analytical theories.
© EPLA 2008