Glassy state of native collagen fibril?
Yerevan Physics Institute - Alikhanian Brothers Street 2, Yerevan 375036, Armenia
2 Institute of Physics, Academia Sinica - Nankang, Taipei 11529, Taiwan
3 Yerevan State Medical University - Koryun Street 2, Yerevan 375025, Armenia
Accepted: 25 May 2011
Our micromechanical experiments show that viscoelastic features of type-I collagen fibril at physiological temperatures display essential dependence on the frequency and speed of heating. For temperatures of 20–30 °C the internal friction has a sharp maximum for a frequency less than 2 kHz. Upon heating the internal friction displays a peak at a temperature Tsoft(v) that essentially depends on the speed of heating v: Tsoft≈70 °C for v=1 °C/min, and Tsoft≈25 °C for v=0.1 °C/min. At the same temperature Tsoft(v) Young's modulus passes through a minimum. All these effects are specific for the native state of the fibril and disappear after heat-denaturation. Taken together with the known facts that the fibril is axially ordered as quasicrystal, but disordered laterally, we interpret our findings as indications of a glassy state, where Tsoft is the softening transition.
PACS: 36.20.-r – Macromolecules and polymer molecules / 36.20.Ey – Conformation (statistics and dynamics) / 05.20.Dd – Kinetic theory
© EPLA, 2011