The dynamics of the DNA denaturation transition
Centrum voor Oppervlaktechemie en Katalyse, KU Leuven - Kasteelpark Arenberg 23, B-3001 Leuven, Belgium, EU
2 Laboratoire de Physique, Ecole Normale Supérieure de Lyon - 46 allée d'Italie, F-69364 Lyon Cedex 07, France, EU
Accepted: 24 April 2012
The dynamics of the DNA denaturation is studied using the Peyrard-Bishop-Dauxois model. The denaturation rate of double stranded polymers decreases exponentially as a function of length below the denaturation temperature. Above Tc, the rate shows a minimum, but then increases as a function of length. We also examine the influence of sequence and solvent friction. Molecules having the same number of weak and strong base-pairs can have significantly different opening rates depending on the order of base-pairs.
PACS: 87.15.H- – Dynamics of biomolecules / 82.20.Pm – Rate constants, reaction cross sections, and activation energies / 87.14.gk – DNA
© EPLA, 2012