Entropy-driven aggregation in multilamellar membranes
Institute for Solid State Physics, University of Tokyo - Kashiwa, Chiba 277-8581, Japan
Received: 15 May 2013
Accepted: 10 June 2013
Membrane-fluctuation–induced attraction between ligand-receptor sites binding neighboring membranes is studied using meshless membrane simulations and the Weil-Farago two-dimensional (2D) lattice model. For the adhesion sites binding two membranes, this entropic interaction is too weak by itself for the adhesion sites to form a large stable domain. However, it is found that this attraction is enhanced sufficiently to induce large domains either when the sites bind three or more neighboring membranes together or have anchors that harden surrounding membranes. These effects are understood by the 2D lattice model with minor extensions.
PACS: 87.16.D- – Membranes, bilayers, and vesicles / 87.15.A- – Theory, modeling, and computer simulation / 82.70.Uv – Surfactants, micellar solutions, vesicles, lamellae, amphiphilic systems, (hydrophilic and hydrophobic interactions)
© EPLA, 2013