Phenomenological theory of a charged polymer molecule in a nanosized gap between two fluidic reservoirs
IBM T.J. Watson Research Center - P.O. Box 218, Yorktown Heights, NY 10598, USA
Received: 17 May 2013
Accepted: 19 September 2013
We use a simple Born ion continuum model to analyse the effect of solvation energy change on the translocation of a charged linear polymer molecule through a nanosized vapor gap between two fluid reservoirs. As the effective radius of the discretely spaced charges increases, our model predicts a transition from trapping to diffusion of the molecule in the vapor gap. We discuss the applicability of our model to single-stranded DNA translocations in gaps, suggest experiments to validate our prediction and propose immediate applications of this new trapping mechanism for slowing down DNA motion for electronic DNA sequencing.
PACS: 82.37.Rs – Single molecule manipulation of proteins and other biological molecules / 81.07.Pr – Organic-inorganic hybrid nanostructures / 85.85.+j – Micro- and nano-electromechanical systems (MEMS/NEMS) and devices
© EPLA, 2013