Predicting self-terminating ventricular fibrillations in an isolated heart
1 Department of Physics and Center for Complex Systems, National Central University Chungli, Taiwan 320, R.O.C.
2 Institute of Physics, Academia Sinica - Nankang, Taipei, Taiwan 115, R.O.C.
3 Institute of Physics, VAST - 10 Dao Tan, Ba Dinh, Hanoi, Vietnam
4 Department of Cell and Molecular Physiology, Loyola University School of Medicine 2160 South First Ave., Maywood, IL 60153, USA
Received: 30 April 2013
Accepted: 15 November 2013
Ventricular fibrillations (VFs) in isolated hearts induced by fast pacing are studied in a Langendorff preparation by measuring the electrical signals from the right atrium and the ventricle . We find that when there is a strong component of Vv detected in Va during VF, the induced VFs are usually not self-terminating. Criteria for the prediction of self-terminating VFs are developed based on the analysis of Vv and Va by the cross-wavelet power spectrum and cross-Fourier power spectrum methods. The success rate of our prediction criteria is about 80–90 %. Our findings suggest that a heart under VF can recover its sinus rhythm only when the sino-atrial node of the heart is not under strong influence of the VF from its ventricle.
PACS: 87.19.Hh – Cardiac dynamics / 82.39.Rt – Reactions in complex biological systems / 05.10.-a – Computational methods in statistical physics and nonlinear dynamics
© EPLA, 2013