Kinetics of the long ssRNA: Steady state
1 Institute of Physics, Academia Sinica - Nankang 11529, Taipei, Taiwan
2 Yerevan State University - 1 A. Manoogian Str., Yerevan 0025, Armenia
Received: 1 March 2014
Accepted: 6 May 2014
The steady state in the kinetic pathways of the long single-strand RNA (ssRNA) in the approximation of a coarse-grained model is studied with analytic calculations. It is assumed that the characteristic time of the secondary-structure rearrangement is much longer than that for the formation of the tertiary structure. The entropy and the specific heat of the system as functions of the temperature are calculated and plotted. A non-equilibrium phase transition of the 2nd order has been observed. The possible biological implication of the obtained results is discussed.
PACS: 87.14.gn – RNA / 87.10.Ca – Analytical theories / 87.15.Cc – Folding: thermodynamics, statistical mechanics, models, and pathways
© EPLA, 2014