Reconciling bond strength of a slip bond at low loading rates with rebinding
1 Department of Engineering Mechanics, Zhejiang University - Hangzhou 310027, China
2 Biomechanics and Biomaterials Lab, Department of Applied Mechanics, Beijing Institute of Technology Beijing 100081, China
Received: 13 January 2015
Accepted: 9 March 2015
Conventional theory predicts that molecular bond strength becomes trivial at very low loading rates, which, however, failed in some experiments probably due to hidden rebinding. Here we propose average bond strength as an alternative physical quantity to be measured in dynamic force spectroscopy experiments. Our analysis indicates that there exists an asymptotic value of average bond strength at low loading rates, which, nevertheless, increases with the spring constant of the loading system. This finding is subsequently confirmed with the Monte Carlo simulation. The proposed average bond strength can be informative in the understanding of the intriguing behaviors of molecular bonds at low loading rates.
PACS: 82.37.Np – Single molecule reaction kinetics, dissociation, etc. / 87.15.A- – Theory, modeling, and computer simulation
© EPLA, 2015