Kinetics of bundle growth in DNA condensation
Department of Chemistry and Biochemistry, University of California Los
Angeles, CA 90095, USA
Accepted: 15 March 1999
Counterion-mediated attractions between like-charged rods lead to macroscopic phase separation at equilibrium, but here we show that the unique kinetics of domain (bundle) growth in this system prevent it from reaching equilibrium. We find an energy barrier to bundle growth that increases linearly with the bundle diameter, which should lead to metastable bundles of a fairly well-defined size.
PACS: 61.20.Qg – Structure of associated liquids: electrolytes, molten salts, etc / 61.25.Hq – Macromolecular and polymer solutions; polymer melts; swelling / 87.15.Nn – Properties of solutions; aggregation and crystallization of macromolecules
© EDP Sciences, 1999