Europhys. Lett.
Volume 67, Number 1, July 2004
Page(s) 137 - 143
Section Interdisciplinary physics and related areas of science and technology
Published online 01 June 2004
Europhys. Lett., 67 (1) , pp. 137-143 (2004)
DOI: 10.1209/epl/i2003-10277-9

Large fluctuations and nonlinear dynamics of birhythmicity

S. Kar and D. S. Ray

Indian Association for the Cultivation of Science - Jadavpur, Kolkata 700 032, India

(Received 21 August 2003; accepted in final form 28 April 2004)

Birhythmicity, which arises due to the simultaneous existence of two stable limit cycles, has been shown to be an interesting dynamical scenario in chemical reactions and biology. Here we present an extension of the Decroly-Goldbeter model for birhythmicity in glycolysis within a Hamiltonian structure incorporating the stochastic substrate injection rate, the critical controlling factor in glycolytic oscillations. Our analysis reveals several generic features of nonlinear dynamics of birhythmicity in the weak-noise limit, e.g., crossover of birhythmicity to monorhythmic behaviour, period-doubling bifurcations leading to chaos and noise-induced transition between attractors.

87.15.Ya - Fluctuations.
87.10.+e - General theory and mathematical aspects.
05.45.-a - Nonlinear dynamics and nonlinear dynamical systems.

© EDP Sciences 2004