Europhys. Lett.
Volume 67, Number 4, August 2004
Page(s) 676 - 682
Section Interdisciplinary physics and related areas of science and technology
Published online 01 August 2004
Europhys. Lett., 67 (4), pp. 676-682 (2004)
DOI: 10.1209/epl/i2004-10103-0

Optimal lift force on vesicles near a compressible substrate

J. Beaucourt, T. Biben and C. Misbah

Laboratoire de Spectrométrie Physique, Université Joseph Fourier (CNRS), Grenoble I B.P. 87, Saint-Martin d'Hères, 38402 Cedex, France

(Received 13 February 2004; accepted in final form 9 June 2004)

The dynamics of vesicles near a compressible substrate mimicking the glycocalyx layer of the internal part of blood vessels reveals the existence of an optimal lift force due to an elasto-hydrodynamic coupling between the counter flow and the deformation of the wall. An estimation of the order of magnitude of the optimal elastic modulus reveals that it lies within the physiological range, which may have important consequences for the dynamic of blood cells (leucocytes or red blood cells).

87.16.Dg - Membranes, bilayers, and vesicles.
83.50.Ha - Flow in channels.
87.17.Jj - Cell locomotion; chemotaxis and related directed motion.

© EDP Sciences 2004