Europhys. Lett.
Volume 73, Number 4, February 2006
Page(s) 628 - 634
Section Interdisciplinary physics and related areas of science and technology
Published online 11 January 2006
Europhys. Lett., 73 (4), pp. 628-634 (2006)
DOI: 10.1209/epl/i2005-10436-0

Single-molecule force spectroscopy: Heterogeneity of chemical bonds

M. Raible and P. Reimann

Universität Bielefeld, Fakultät für Physik - 33615 Bielefeld, Germany

received 9 November 2005; accepted in final form 21 December 2005
published online 11 January 2006

We show that the standard theoretical framework in single-molecule force spectroscopy by Evans and Ritchie (Biophys. J., 72 (1997) 1541) has to be extended in order to consistently describe the experimental findings. The basic new concept is to take into account heterogeneity of the chemical bonds, resulting in excellent agreement between theory and experiment.

82.37.Np - Single molecule reaction kinetics, dissociation, etc.
33.15.Fm - Bond strengths, dissociation energies.
87.15.By - Structure and bonding.

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