Sharp DNA denaturation due to solvent interactionG. Weber
School of Chemistry, University of Southampton - Southampton, SO17 1BJ, UK
received 17 November 2005; accepted in final form 13 January 2006
published online 1 February 2006
Within the framework of the Peyrard-Bishop model for DNA melting, sharp denaturation temperature profiles can currently be obtained only if anharmonic base-pair stacking interactions are considered. We show that, when solvent interactions are included, a sharp denaturation of the DNA double helix is obtained without the need for anharmonic nearest-neighbor interactions. Using the concept of pseudo-Schrödinger equations we discuss the analogy of these transition to quantum-mechanical tunneling, and in particular we show that the sharp transitions are similar to resonant tunneling.
87.14.Gg - DNA, RNA.
87.15.Aa - Theory and modeling; computer simulation.
05.70.Fh - Phase transitions: general studies.
© EDP Sciences 2006