How to build nanoblocks using DNA scaffoldsN. A. Licata1, 2 and A. V. Tkachenko1
1 Department of Physics and Michigan Center for Theoretical Physics, University of Michigan 450 Church Str., Ann Arbor, MI 48109 USA
2 Max Planck Institue for the Physics of Complex Systems - Nöthnitzerstrasse 38, 01187 Dresden, Germany, EU
received 2 June 2008; accepted in final form 12 September 2008; published October 2008
published online 14 October 2008
In recent years there have been a number of proposals to utilize the specificity of DNA-based interactions for potential applications in nanoscience. One interesting direction is the self-assembly of micro- and nanoparticle clusters using DNA scaffolds. In this letter we consider a DNA scaffold method to self-assemble clusters of “colored" particles. Stable clusters of identical microspheres have recently been produced by an entirely different method. Our DNA-based approach self-assembles clusters with additional degrees of freedom associated with particle permutation. We demonstrate that in the non-equilibrium regime of irreversible binding the self-assembly process is experimentally feasible. These color degrees of freedom may allow for more diverse intercluster interactions essential for hierarchical self-assembly of larger structures.
05.65.+b - Self-organized systems.
05.70.Ln - Nonequilibrium and irreversible thermodynamics.
61.46.-w - Structure of nanoscale materials.
© EPLA 2008