Volume 85, Number 5, March 2009
Article Number 58006
Number of page(s) 6
Section Interdisciplinary Physics and Related Areas of Science and Technology
Published online 20 March 2009
EPL, 85 (2009) 58006
DOI: 10.1209/0295-5075/85/58006

Dynamics of forced biopolymer translocation

V. V. Lehtola, R. P. Linna and K. Kaski

Department of Biomedical Engineering and Computational Science, Helsinki University of Technology P.O. Box 9203, FIN-02015 TKK, Finland, EU

received 9 October 2008; accepted in final form 19 February 2009; published March 2009
published online 20 March 2009

We present results from our simulations of biopolymer translocation in a solvent which explain the main experimental findings. The forced translocation can be described by simple force balance arguments for the relevant range of pore potentials in experiments and biological systems. Scaling of translocation time with polymer length varies with pore force and friction. Hydrodynamics affects this scaling and significantly reduces translocation times.

87.15.-v - Biomolecules: structure and physical properties.
82.35.Lr - Physical properties of polymers.
87.15.A- - Theory, modeling, and computer simulation.

© EPLA 2009