Volume 88, Number 1, October 2009
Article Number 18001
Number of page(s) 6
Section Interdisciplinary Physics and Related Areas of Science and Technology
Published online 14 October 2009
EPL, 88 (2009) 18001
DOI: 10.1209/0295-5075/88/18001

Global cross-over dynamics of single semiflexible polymers

M. Hinczewski and R. R. Netz

Department of Physics, Technical University of Munich - 85748 Garching, Germany, EU

received 23 July 2009; accepted in final form 16 September 2009; published October 2009
published online 14 October 2009

We present a mean-field dynamical theory for single semiflexible polymers which can precisely capture, without fitting parameters, recent fluorescence correlation spectroscopy results on single-monomer kinetics of DNA strands in solution. Our approach works globally, covering three decades of strand length and five decades of time: it includes the complex cross-overs occurring between stiffness-dominated and flexible bending modes, along with larger-scale rotational and center-of-mass motion. The accuracy of the theory stems in part from long-range hydrodynamic coupling between the monomers, which makes a mean-field description more realistic. Its validity extends even to short, stiff fragments, where we also test the theory through Brownian hydrodynamics simulations.

87.15.H- - Dynamics of biomolecules.
87.14.gk - DNA.
82.35.Lr - Physical properties of polymers.

© EPLA 2009