Volume 88, Number 6, December 2009
Article Number 68001
Number of page(s) 5
Section Interdisciplinary Physics and Related Areas of Science and Technology
Published online 01 December 2009
EPL, 88 (2009) 68001
DOI: 10.1209/0295-5075/88/68001

Energy transfer in nonlinear network models of proteins

F. Piazza1 and Y.-H. Sanejouand2

1   Ecole Polytechnique Fédérale de Lausanne, Laboratoire de Biophysique Statistique, ITP-SB - BSP-720, CH-1015 Lausanne, Switzerland
2   Laboratoire U3B, UMR 6204 du CNRS, Faculté des Sciences et des Techniques - 2, rue de la Houssinière, 44322 Nantes Cedex 3, France, EU

received 19 October 2009; accepted in final form 18 November 2009; published December 2009
published online 21 December 2009

We investigate how nonlinearity and topological disorder affect the energy relaxation of local kicks in coarse-grained network models of proteins. We find that nonlinearity promotes long-range, coherent transfer of substantial energy to specific functional sites, while depressing transfer to generic locations. In some cases, transfer is mediated by the self-localization of discrete breathers at distant locations from the kick, acting as efficient energy-accumulating centers.

87.15.-v - Biomolecules: structure and physical properties.
63.20.Pw - Localized modes.
05.45.-a - Nonlinear dynamics and chaos.

© EPLA 2009