Volume 43, Number 4, August II 1998
|Page(s)||363 - 368|
|Published online||01 September 2002|
Stochastic feedback and the regulation of biological rhythms
Center for Polymer Studies and Department of Physics,
Boston University Boston, MA 02215, USA
2 Department of Physics, Massachusetts Institute of Technology Cambridge, MA 02139, USA
3 Cardiovascular Division, Harvard Medical School Beth Israel Hospital, Boston, MA 02215, USA
Accepted: 26 June 1998
We propose a general approach to the question of how biological rhythms spontaneously self-regulate, based on the concept of “stochastic feedback”. We illustrate this approach by considering at a coarse-grained level the neuroautonomic regulation of the heart rate. The model generates complex dynamics and successfully accounts for key characteristics of cardiac variability, including the 1/f power spectrum, the functional form and scaling of the distribution of variations, and correlations in the Fourier phases indicating nonlinear dynamics.
PACS: 02.50.Ey – Stochastic processes / 05.40.+j – Fluctuation phenomena, random processes, and Brownian motion / 05.45.+b – Theory and models of chaotic systems
© EDP Sciences, 1998
Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.
Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.
Initial download of the metrics may take a while.