| Issue |
Europhys. Lett.
Volume 50, Number 6, June II 2000
|
|
|---|---|---|
| Page(s) | 756 - 761 | |
| Section | Condensed matter: structure, mechanical and thermal properties | |
| DOI | https://doi.org/10.1209/epl/i2000-00545-8 | |
| Published online | 01 September 2002 | |
On the helix-coil transition in grafted chains
UMR 5819, DRFMC/SI3M, CEA-Grenoble - 17, rue des Martyrs
38054 Grenoble Cedex 9, France
Received:
15
November
1999
Accepted:
20
April
2000
The helix-coil transition is modified by grafting to a surface. This modification is studied for short peptides capable of forming α-helices. Three factors are involved: i) the grafting can induce change of the boundary free energy of the helical domain ii) the van der Waals attraction between the helices and iii) the crowding-induced stretching of the coils. As a result, the helix-coil transition acquires “all or nothing” characteristics. In addition the transition temperature is elevated and the transition itself sharpens as the grafting density increases.
PACS: 61.25.Hq – Macromolecular and polymer solutions; polymer melts; swelling / 87.15.-v – Biomolecules: structure and physical properties / 87.15.He – Dynamics and conformational changes
© EDP Sciences, 2000
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