Volume 52, Number 5, December I 2000
|Page(s)||511 - 517|
|Section||Atomic and molecular physics|
|Published online||01 September 2002|
Stretching tethered DNA chains in shear flow
Laboratoire Physico-Chimie Curie (UMR CNRS 168)
Institut Curie Section de Recherche -
26 rue d'Ulm, 75230 Paris cedex 05, France
Corresponding author: email@example.com
Accepted: 25 September 2000
We discuss the stretching of tethered chains subject to a shear flow. Fluorescence microscopy measurements of the extension of sheared tethered DNA, “model polymers”, of various lengths are presented. The tethered chains approach full extension as the flow rate is increased, but very slowly. We show that a general theory to understand the large deformation of any sheared tethered chain must include both the correct nonlinear force-extension relation and chain fluctuations transverse to the flow direction, which themselves depend on the nonlinear elasticity of the chain. Direct comparison of derived scaling laws to simulations and experiments support our theory.
PACS: 36.20.-r – Macromolecules and polymer molecules / 87.15.-v – Biomolecules: structure and physical properties / 47.50.+d – Non-Newtonian fluid flows
© EDP Sciences, 2000
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