Volume 57, Number 5, March 2002
|Page(s)||745 - 751|
|Section||Interdisciplinary physics and related areas of science and technology|
|Published online||01 September 2002|
Quasispecies evolution in general mean-field landscapes
Institute for Theoretical Physics, University of
Santa Barbara CA 93106-4030, USA
Corresponding author: firstname.lastname@example.org
Accepted: 6 December 2001
I consider a class of fitness landscapes, in which the fitness is a function of a finite number of phenotypic “traits”, which are themselves linear functions of the genotype. I show that the stationary trait distribution in such a landscape can be explicitly evaluated in a suitably defined “thermodynamic limit”, which is a combination of infinite-genome and strong selection limits. These considerations can be applied in particular to identify relevant features of the evolution of promoter binding sites, in spite of the shortness of the corresponding sequences.
PACS: 87.10.+e – Biological and medical physics: General theory and mathematical aspects / 87.23.-n – Ecology and evolution
© EDP Sciences, 2002
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