| Issue |
Europhys. Lett.
Volume 68, Number 3, November 2004
|
|
|---|---|---|
| Page(s) | 398 - 404 | |
| Section | Electromagnetism, optics, acoustics, heat transfer, classical mechanics, and fluid dynamics | |
| DOI | https://doi.org/10.1209/epl/i2004-10211-9 | |
| Published online | 16 October 2004 | |
Deformation of vesicles flowing through capillaries
Laboratoire de Spectrométrie Physique, CNRS-Université Joseph Fourier, Grenoble I B.P. 87, 38402 Saint-Martin d'Hères, France
Corresponding author: thomas.podgorski@ujf-grenoble.fr
Received:
23
April
2004
Accepted:
3
September
2004
The flow of giant lipid vesicles through cylindrical capillaries
is experimentally investigated. Vesicles are deflated with
reduced volumes between 0.8 and 1, corresponding to prolate
spheroidal equilibrium shapes. Both interior and exterior fluids
are sugar solutions with viscosities close to
10-3
. Vesicles are aspirated into a capillary tube
with a diameter close to the vesicle size and a constant flow
rate is imposed. Significant deformation of the membrane occurs
and increases when the velocity, confinement or deflation of the
vesicle are increased. The mobility of vesicles, defined as the
ratio of their velocity to the average velocity of the fluid is a
decreasing function of confinement. Our experimental system
provides a controllable and flexible tool to investigate
deformability effects responsible for crucial aspects of blood
rheology in capillaries.
PACS: 47.55.Kf – Multiphase and particle-laden flows / 87.19.Tt – Rheology of body fluids / 83.50.Ha – Flow in channels
© EDP Sciences, 2004
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