| Issue |
Europhys. Lett.
Volume 72, Number 2, October 2005
|
|
|---|---|---|
| Page(s) | 301 - 307 | |
| Section | Interdisciplinary physics and related areas of science and technology | |
| DOI | https://doi.org/10.1209/epl/i2005-10225-9 | |
| Published online | 14 September 2005 | |
Four-states phase diagram of proteins
Équipe de Dynamique des Assemblages Membranaires, UMR CNRS 7565 Faculté des Sciences, Université Henri Poincaré-Nancy 1 54506 Vandoeuvre-lès-Nancy, France
Received:
19
April
2005
Accepted:
16
August
2005
A four-states phase diagram for protein folding as a function of temperature and solvent quality is derived from an improved 2d lattice model taking into account the temperature dependence of the hydrophobic effect. The phase diagram exhibits native, globule and two coil-type regions. In agreement with experiment, the model reproduces the phase transitions indicative of both warm and cold denaturations. Finally, it predicts transitions between the two coil states and a critical point.
PACS: 87.14.Ee – Proteins / 64.70.-p – Specific phase transitions / 87.15.Aa – Theory and modeling; computer simulation
© EDP Sciences, 2005
Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.
Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.
Initial download of the metrics may take a while.