Volume 73, Number 5, March 2006
|Page(s)||806 - 811|
|Section||Interdisciplinary physics and related areas of science and technology|
|Published online||01 February 2006|
Sharp DNA denaturation due to solvent interaction
School of Chemistry, University of Southampton - Southampton, SO17 1BJ, UK
Corresponding author: G.Weber@soton.ac.uk
Accepted: 13 January 2006
Within the framework of the Peyrard-Bishop model for DNA melting, sharp denaturation temperature profiles can currently be obtained only if anharmonic base-pair stacking interactions are considered. We show that, when solvent interactions are included, a sharp denaturation of the DNA double helix is obtained without the need for anharmonic nearest-neighbor interactions. Using the concept of pseudo-Schrödinger equations we discuss the analogy of these transition to quantum-mechanical tunneling, and in particular we show that the sharp transitions are similar to resonant tunneling.
PACS: 87.14.Gg – DNA, RNA / 87.15.Aa – Theory and modeling; computer simulation / 05.70.Fh – Phase transitions: general studies
© EDP Sciences, 2006
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