| Issue |
EPL
Volume 77, Number 6, March 2007
|
|
|---|---|---|
| Article Number | 68005 | |
| Number of page(s) | 6 | |
| Section | Interdisciplinary Physics and Related Areas of Science and Technology | |
| DOI | https://doi.org/10.1209/0295-5075/77/68005 | |
| Published online | 06 March 2007 | |
Theory of the length distribution of tread-milling actin filaments inside bundles
Department of Chemical Physics, The Weizmann Institute of Science - P.O.B. 26, Rehovot, Israel 76100
Received:
11
July
2006
Accepted:
26
January
2007
The length distribution of tread-milling actin filaments has been measured in vitro, in the presence of severing and cross-linking proteins. The cross-linking proteins induce the formation of bundles, and we present here a kinetic model for this system which takes into account the inherent asymmetry and non-equilibrium nature of the tread-milling actin filaments. The effects of actin cross-linkers is to make the length distribution of filaments inside bundles narrower compared to free filaments. We get good agreement with the available experimental data.
PACS: 87.16.Ka – Filaments, microtubules, their networks, and supramolecular assemblies / 87.15.Nn – Properties of solutions; aggregation and crystallization of macromolecules
© Europhysics Letters Association, 2007
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