Volume 80, Number 1, October 2007
|Number of page(s)||6|
|Section||Interdisciplinary Physics and Related Areas of Science and Technology|
|Published online||07 September 2007|
Surface-enhanced unfolding of collapsed polymers in shear flow
Physics Department, TU Munich - D-85748 Garching, Germany
2 Laboratoire Matière Molle & Chimie, ESPCI, CNRS, UMR 7167 - 10 rue Vauquelin, 75005 Paris, France
Accepted: 14 August 2007
Using hydrodynamic simulations we study the shear-induced unfolding of a collapsed polymer near a planar wall. Above a well-defined threshold shear rate , the globule becomes unstable and displays stretching-refolding events. With decreasing distance from the surface, the critical shear rate goes down, which is rationalized within a scaling analysis in terms of increased hydrodynamic stress due to a surface-induced slowing-down of globule rotation and translation. Our results are relevant for protein-assisted blood clotting in capillary vessels.
PACS: 87.15.-v – Biomolecules: structure and physical properties / 82.37.-j – Single molecule kinetics
© Europhysics Letters Association, 2007
Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.
Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.
Initial download of the metrics may take a while.