Volume 84, Number 1, October 2008
|Number of page(s)||6|
|Section||Interdisciplinary Physics and Related Areas of Science and Technology|
|Published online||25 September 2008|
Nanofluidics in cellular tubes under oscillatory extension
Physico-Chimie Curie, Institut Curie, Section de Recherche - 26 rue d'Ulm, 75248 Paris Cedex 05, France, EU
2 Department of Physics and Astronomy, The University of California at Los Angeles Los Angeles 90095-1569, CA, USA
Accepted: 22 August 2008
Membrane nanotubes or tethers extruded from cells exhibit dynamic features that are believed to exhibit viscoelastic rheological properties. We have performed typical microrheology experiments on tethers pulled from red blood cells by measuring the force response to small oscillatory extensions or compressions. Our data, supported by a simple theoretical model, show that the force response does not reflect any intrinsic viscoelastic properties of the tethers themselves, but instead is dominated by the drainage of the internal cellular fluid into and out of the oscillating nanoconduit over a frequency-dependent penetration depth. The simplicity of tether rheology suggests its usage as a probe for measuring the local viscosity of the cytosol near the plasma membrane.
PACS: 87.85.gf – Fluid mechanics and rheology / 87.16.dm – Mechanical properties and rheology / 47.60.Dx – Flows in ducts and channels
© EPLA, 2008
Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.
Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.
Initial download of the metrics may take a while.