Issue |
EPL
Volume 85, Number 1, January 2009
|
|
---|---|---|
Article Number | 18006 | |
Number of page(s) | 5 | |
Section | Interdisciplinary Physics and Related Areas of Science and Technology | |
DOI | https://doi.org/10.1209/0295-5075/85/18006 | |
Published online | 07 January 2009 |
Detection of DNA hybridisation on a functionalised diamond surface using reflection anisotropy spectroscopy
1
Department of Physics, University of Liverpool - Liverpool, L69 7ZE, UK, EU
2
School of Biological Sciences, University of Liverpool - Liverpool, L69 7ZB, UK, EU
3
Code 6174, Naval Research Laboratory - Washington, DC 20375, USA
4
Chemistry Department, University of Wisconsin-Madison - 1101 University Avenue Madison, WI 53706 USA
Corresponding author: peterw@liverpool.ac.uk
Received:
23
October
2008
Accepted:
28
November
2008
The analysis of single-stranded DNA attached to a polycrystalline diamond surface by reflection anisotropy spectroscopy (RAS) demonstrates that the DNA is oriented essentially vertically to the surface. RAS is able to detect the hybridisation between the attached strand and the homologous sequence.
PACS: 87.80.Dj – Spectroscopies / 81.05.Uw – Carbon, diamond, graphite / 87.14.gk – DNA
© EPLA, 2009
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