Volume 85, Number 6, March 2009
|Number of page(s)||6|
|Section||Interdisciplinary Physics and Related Areas of Science and Technology|
|Published online||01 April 2009|
Charge transport in bacteriorhodopsin monolayers: The contribution of conformational change to current-voltage characteristics
Dipartimento di Ingegneria dell'Innovazione, Università del Salento - via Arnesano, I-73100 Lecce, Italy, EU
2 CNISM, Consorzio Nazionale Interuniversitario per le Scienze Fisiche della Materia via della Vasca Navale 84, I-00146 Roma, Italy, EU
Corresponding author: firstname.lastname@example.org
Accepted: 23 February 2009
When moving from native to light-activated bacteriorhodospin, modification of charge transport consisting of an increase of conductance is correlated to the protein conformational change. A theoretical model based on a map of the protein tertiary structure into a resistor network is implemented to account for a sequential tunneling mechanism of charge transfer through neighbouring amino acids. The model is validated by comparison with current-voltage experiments. The predictability of the model is further tested on bovine rhodopsin, a G-protein coupled receptor (GPCR) also sensitive to light. In this case, results show an opposite behaviour with a decrease of conductance in the presence of light.
PACS: 87.85.jc – Electrical, thermal, and mechanical properties of biological matter / 87.15.hp – Conformational changes / 87.10.Rt – Monte Carlo simulations
© EPLA, 2009
Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.
Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.
Initial download of the metrics may take a while.