Volume 86, Number 4, May 2009
|Number of page(s)||6|
|Published online||29 May 2009|
Two-state flashing molecular pump
Facultat de Física, Universitat de Barcelona - Diagonal 647, Barcelona, Spain, EU
Accepted: 27 April 2009
Here we study a pumping device capable of maintaining a density gradient and a flux of particles across a membrane. Its driving mechanism is based on the flashing ratchet effect powered by the random telegraph process in the presence of thermal fluctuations. Unlike Brownian motors, the concentrations at both reservoir boundaries need to be implemented as boundary conditions. The residence transition rates of the dichotomic flashing are related to the binding and hydrolysis of ATP molecules. The model is exactly solved and explored. The pump energetics is discussed and the relevant parameter values are tuned within a biological scale.
PACS: 05.40.-a – Fluctuation phenomena, random processes, noise, and Brownian motion / 05.10.Gg – Stochastic analysis methods (Fokker-Planck, Langevin, etc.) / 87.16.A- – Theory, modeling, and simulations
© EPLA, 2009
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