Volume 91, Number 2, July 2010
|Number of page(s)||6|
|Section||Interdisciplinary Physics and Related Areas of Science and Technology|
|Published online||05 August 2010|
Cohesive suction-cup force in cell separation dynamics
PSC - 33 rue St Leu, 80039 Amiens Cedex, France, EU
Accepted: 29 June 2010
When an external pulling force is applied onto a cell stuck to its substrate, a reacting “suction-cup” force, due to the slow penetration of the surrounding fluid between the cell and the substrate, opposes to the separation. It can overcome other known adhesive forces when the process is sufficiently violent (typically 105 N/m2). The physical origin of this effect may be compared with that leaning a suction-cup against a bathroom wall. We address the consequences of this effect on i) the separation energy, ii) the fluid motion surrounding the cell, and iii) the inhibition of cell motion.
PACS: 87.10.Ca – Analytical theories / 87.17.Rt – Cell adhesion and cell mechanics
© EPLA, 2010
Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.
Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.
Initial download of the metrics may take a while.