Volume 102, Number 4, May 2013
|Number of page(s)||6|
|Section||Interdisciplinary Physics and Related Areas of Science and Technology|
|Published online||11 June 2013|
Iterative reconstruction for few-view grating-based phase-contrast CT —An in vitro mouse model
1 Zentralinstitut für Medizintechnik, Technische Universität München - Boltzmannstr 11, 85748 Garching, Germany, EU
2 Department of Physics, Technische Universität München - James-Franck-Str. 1, 85748 Garching, Germany, EU
3 Department of Radiology, Technische Universität München - Ismaninger Str. 22, 81675 Munich, Germany, EU
Received: 15 January 2013
Accepted: 13 May 2013
The aim of this work is to investigate the improvement of image quality in few-view grating-based phase-contrast computed tomography (PCCT) applications via compressed sensing (CS) inspired iterative reconstruction on an in vitro mouse model. PCCT measurements are performed on a grating-based PCCT setup using a high-brilliance synchrotron source and a conventional tube source. The sampling density of the data is reduced by a factor of up to 20 and iteratively reconstructed. It is demonstrated that grating-based PCCT intrinsically meets the major conditions for a successful application of CS. Contrast fidelity and the reproduction of details is presented in all reconstructed objects. The feasibility of the iterative reconstruction on data generated with a conventional X-ray source is illustrated on a fluid phantom and a mouse specimen, undersampled by a factor of up to 20.
PACS: 87.57.nf – Reconstruction / 87.57.Q- – Computed tomography / 87.64.mh – Phase contrast and DIC
© EPLA, 2013
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