Volume 114, Number 1, April 2016
|Number of page(s)
|Electromagnetism, Optics, Acoustics, Heat Transfer, Classical Mechanics, and Fluid Dynamics
|03 May 2016
Scaling of shear-induced diffusion and clustering in a blood-like suspension
1 Computational Science Lab, University of Amsterdam - Science Park 904, 1098 XH, Amsterdam, The Netherlands
2 Electric Ant Lab B.V. - Panamalaan 4K, 1019AZ, Amsterdam, The Netherlands
3 ITMO University - Saint-Petersburg, Russian Federation
Received: 24 September 2015
Accepted: 20 April 2016
The transport of cells and substances in dense suspensions like blood heavily depends on the microstructure and the dynamics arising from their interactions with red blood cells (RBCs). Computer simulations are used to probe into the detailed transport-related characteristics of a blood-like suspension, for a wide range of volume fractions and shear rates. The shear-induced diffusion of RBCs does not follow the established linear scaling with shear rate for higher volume fractions. The properties directly related to RBC deformability —stretching and flow orientation— are not sufficient to explain this departure according to the model of Breedveld, pointing to the dominance of collective effects in the suspension. A cluster size analysis confirms that collective effects dominate high volume fractions, as the mean cluster size is above 2 and the number of “free RBCs” is significantly decreased in denser suspensions. The mean duration of RBC contacts in clusters is increased in the high volume fraction and shear rate cases, showing that these clusters live longer.
PACS: 47.57.E- – Suspensions / 47.63.-b – Biological fluid dynamics / 47.61.Jd – Multiphase flows
© EPLA, 2016
Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.
Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.
Initial download of the metrics may take a while.