Volume 133, Number 1, January 2021
|Number of page(s)||6|
|Section||Physics of Gases, Plasmas and Electric Discharges|
|Published online||04 March 2021|
Cold-atmospheric-plasma-induced skin wrinkle
1 State Key Laboratory for Geomechanics and Deep Underground Engineering, School of Mechanics and Civil Engineering, China University of Mining and Technology - Xuzhou, Jiangsu, 221116, China
2 Department of Mechanical and Aerospace Engineering, The George Washington University Washington, DC 20052, USA
3 Department of Mechanical and Aerospace Engineering, University of California - Los Angeles, CA 90095, USA
Received: 21 October 2020
Accepted: 2 December 2020
The biomedical applications of cold atmospheric plasma (CAP) involve diverse multidisciplinary approaches and are based on the plasma interactions with tissues/cells and other biomaterials. Recently, we have implemented experiments for plasma-tissue interactions and first observe CAP-induced skin wrinkling behavior. The plasma-induced wrinkling behavior during the CAP interaction with a mouse's skin is explored through theoretical modeling and numerical simulation. It is found that the critical strain decreases with the increase of the elastic modulus ratio of the equivalent film-substrate model. The change of the elastic modulus ratio will lead to different surface morphology, which infers a suitable way to diagnose skin diseases. In addition, surface morphologies with similar wavelength but larger amplitude can be observed for a larger radius of curvature. These results might help the plasma community to understand the CAP-induced wrinkling phenomenon and stimulate extensive discussions on studies on plasma-tissue/biomaterials interactions.
PACS: 52.77.-j – Plasma applications
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