Issue |
EPL
Volume 137, Number 5, March 2022
|
|
---|---|---|
Article Number | 51001 | |
Number of page(s) | 7 | |
Section | Statistical physics and networks | |
DOI | https://doi.org/10.1209/0295-5075/ac5cdb | |
Published online | 09 May 2022 |
The interplay between diversity and noise in an excitable cell network model
1 National Institute of Chemical Physics and Biophysics - Akadeemia tee 23, 12618 Tallinn, Estonia
2 Department of Engineering, Università Campus Bio-Medico di Roma - Via Á. del Portillo 21, 00128 Rome, Italy
(a) stefano.scialla@kbfi.ee (corresponding author)
(b) marco.patriarca@kbfi.ee
(c) els.heinsalu@kbfi.ee
Received: 18 November 2021
Accepted: 11 March 2022
We study the effects of the interplay between diversity and noise in a 3D network of FitzHugh-Nagumo elements, with topology and dimensions chosen to model a pancreatic β-cell cluster, as an example of an excitable cell network. Our results show that diversity and noise are non-equivalent sources of disorder that have different effects on the network dynamics: their synchronization mechanisms may act independently of one another or synergistically, depending on the mean value of the diversity distribution compared to the intrinsic oscillatory range of the network elements.
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