Electrophoretic mobility of heterogeneous vesicles
Laboratoire de Physico-Chimie Théorique, ESA CNRS 7083, ESPCI
10 rue Vauquelin, F-75231 Paris Cedex 05, France
Accepted: 1 March 1999
Unlike rigid uniformly charged particles, vesicles bearing transmembrane inclusions undergo, under electrophoretic motion, a redistribution of their surface charges. We study how this internal response of the vesicle affects its electrophoretic mobility, which is shown to depend on the vesicle size, on the average inclusion concentration and on the field intensity. The surface reorganization of the inclusions may cause the mobility to change sign as the field is increased. From our analysis, free-flow fractionation methods can be envisaged.
PACS: 82.45.+z – Electrochemistry and electrophoresis / 87.16.Dg – Membranes, bilayers, and vesicles / 82.70.-y – Disperse systems
© EDP Sciences, 1999