Europhys. Lett.
Volume 70, Number 1, April 2005
Page(s) 49 - 55
Section General
Published online 09 March 2005
Europhys. Lett., 70 (1), pp. 49-55 (2005)
DOI: 10.1209/epl/i2004-10456-2

Phenomenological energetics for molecular motors

T. Harada

Department of Physics, Graduate School of Science, Kyoto University Kyoto 606-8502, Japan

received 3 November 2004; accepted in final form 31 January 2005
published online 9 March 2005

A phenomenologically closed framework is presented to evaluate the energy balance on a molecular motor at a nonequilibrium steady state. We employed a generalized Langevin equation as a coarse-grained model of a motor, based on which the efficiency of the motor can be calculated from macroscopic observables alone. It is shown that the energy fluxes at a nonequilibrium steady state are related to the extent of the violation of fluctuation-dissipation relation for the velocity fluctuation. We show that the present framework adequately explains the recent experimental result for kinesin.

05.40.Jc - Brownian motion.
05.70.Ln - Nonequilibrium and irreversible thermodynamics.
87.16.Nn - Motor proteins (myosin, kinesin dynein).

© EDP Sciences 2005