Phenomenological energetics for molecular motorsT. Harada
Department of Physics, Graduate School of Science, Kyoto University Kyoto 606-8502, Japan
received 3 November 2004; accepted in final form 31 January 2005
published online 9 March 2005
A phenomenologically closed framework is presented to evaluate the energy balance on a molecular motor at a nonequilibrium steady state. We employed a generalized Langevin equation as a coarse-grained model of a motor, based on which the efficiency of the motor can be calculated from macroscopic observables alone. It is shown that the energy fluxes at a nonequilibrium steady state are related to the extent of the violation of fluctuation-dissipation relation for the velocity fluctuation. We show that the present framework adequately explains the recent experimental result for kinesin.
05.40.Jc - Brownian motion.
05.70.Ln - Nonequilibrium and irreversible thermodynamics.
87.16.Nn - Motor proteins (myosin, kinesin dynein).
© EDP Sciences 2005