Volume 45, Number 3, February 1999
|Page(s)||283 - 289|
|Published online||01 September 2002|
Force-velocity relations of a two-state crossbridge model for molecular motors
Institut für Theoretische Physik, Technische Universität
München D-85747 Garching, Germany
2 Physics Department, Harvard University - Cambridge, MA02138, USA
Accepted: 26 November 1998
We discuss the force-velocity relations obtained in a two-state crossbridge model for molecular motors. They can be calculated analytically in two limiting cases: for a large number and for one pair of motors. The effect of the strain-dependent detachment rate on the motor characteristics is studied. It can lead to linear, myosin-like, kinesin-like and anomalous curves. In particular, we specify the conditions under which oscillatory behavior may be found.
PACS: 05.40.+j – Fluctuation phenomena, random processes, and Brownian motion / 87.10.+e – Biological and medical physics: General theory and mathematical aspects / 87.22.Jb – Muscle contraction, nerve conduction, synaptic transmission, memorization, and other neurophysiological processes (excluding perception processes and speech)
© EDP Sciences, 1999
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