Volume 67, Number 4, August 2004
|Page(s)||676 - 682|
|Section||Interdisciplinary physics and related areas of science and technology|
|Published online||01 August 2004|
Optimal lift force on vesicles near a compressible substrate
Laboratoire de Spectrométrie Physique, Université Joseph Fourier (CNRS), Grenoble I B.P. 87, Saint-Martin d'Hères, 38402 Cedex, France
Accepted: 9 June 2004
The dynamics of vesicles near a compressible substrate mimicking the glycocalyx layer of the internal part of blood vessels reveals the existence of an optimal lift force due to an elasto-hydrodynamic coupling between the counter flow and the deformation of the wall. An estimation of the order of magnitude of the optimal elastic modulus reveals that it lies within the physiological range, which may have important consequences for the dynamic of blood cells (leucocytes or red blood cells).
PACS: 87.16.Dg – Membranes, bilayers, and vesicles / 83.50.Ha – Flow in channels / 87.17.Jj – Cell locomotion; chemotaxis and related directed motion
© EDP Sciences, 2004
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