Volume 71, Number 5, September 2005
|Page(s)||859 - 865|
|Section||Interdisciplinary physics and related areas of science and technology|
|Published online||27 July 2005|
Lateral diffusion of a protein on a fluctuating membrane
II. Institut für Theoretische Physik, Universität Stuttgart - 70550 Stuttgart, Germany
Accepted: 27 June 2005
Measurements of lateral diffusion of proteins in a membrane typically assume that the movement of the protein occurs in a flat plane. Real membranes, however, are subject to thermal fluctuations, leading to movement of an inclusion into the third dimension. We calculate the magnitude of this effect by projecting real three-dimensional diffusion onto an effective one on a flat plane. We consider both a protein that is free to diffuse in the membrane and one that also couples to the local curvature. For a freely diffusing inclusion the measured projected diffusion constant is up to 15% smaller than the actual value. Coupling to the curvature enhances diffusion significantly up to a factor of two.
PACS: 87.15.Vv – Diffusion / 87.16.Dg – Membranes, bilayers, and vesicles / 05.40.-a – Fluctuation phenomena, random processes, noise, and Brownian motion
© EDP Sciences, 2005
Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.
Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.
Initial download of the metrics may take a while.