Issue |
Europhys. Lett.
Volume 75, Number 4, August 2006
|
|
---|---|---|
Page(s) | 659 - 665 | |
Section | Interdisciplinary physics and related areas of science and technology | |
DOI | https://doi.org/10.1209/epl/i2006-10150-5 | |
Published online | 14 July 2006 |
Tension-induced pore formation and leakage in adhering vesicles
1
Philipps-Universität Marburg, Fachbereich Physik - Renthof 5 D-35032 Marburg, Germany
2
Department of Chemistry, Stanford University - Stanford, CA 94305, USA
3
Department of Physiology and Biophysics, University of Colorado Health Sciences Center - Denver, CO 80045, USA
Received:
18
February
2006
Accepted:
27
June
2006
The influence of inclusion-induced tension on pore formation is studied theoretically and experimentally. It is shown that fluorescently labeled lipids can enhance pore formation and induce leakage of adhering vesicles. These effects are more pronounced for smaller vesicles. The theoretical predictions are confirmed by experimental two-color fluorescent data. Finally, the influence of the pore formation dynamics on rupture processes of vesicles is analyzed yielding a new picture of the transition to bilayer disks.
PACS: 87.16.Dg – Membranes, bilayers, and vesicles / 68.35.Np – Adhesion
© EDP Sciences, 2006
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