Volume 46, Number 1, April I 1999
|Page(s)||107 - 113|
|Section||Cross-disciplinary physics and related areas of science and technology|
|Published online||01 September 2002|
Influence of specific ionic diffusion on the protein self-aggregation instability
Laboratoire de Physique des Solides, URA 02 CNRS,
Bât. 510 Université Paris Sud 91405 Orsay Cedex, France
2 CEA Grenoble, Département de biologie moléculaire et structurale 17 rue des martyrs, 38054 Grenoble Cedex 9, France
Accepted: 18 January 1999
Transcellular currents are involved in the generation of spatial order during the growth of numerous biological cells. A dynamic instability triggered by the aggregation of the proteins may be at the origin of the symmetry breaking. An analysis in terms of a semi-microscopic model is performed. It reveals that the dynamics of the ion transferred by the mobile proteins, pumps or channels, is of paramount importance. The diffusion currents play a crucial role in the critical behaviour, even if the instability mechanism is of electric origin. When the diffusion coefficients of the different species are different, our results do not agree with those of the classical cable formalism.
PACS: 87.10.+e – General theory and mathematical aspects / 47.20.-k – Hydrodynamic stability / 66.10.-x – Diffusion and ionic conduction in liquids
© EDP Sciences, 1999
Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.
Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.
Initial download of the metrics may take a while.