Volume 89, Number 4, February 2010
|Number of page(s)||6|
|Section||Interdisciplinary Physics and Related Areas of Science and Technology|
|Published online||03 March 2010|
Effects of Parkinson's disease on brain-wave phase synchronisation and cross-modulation
Institut für Physik, Martin-Luther-Universität Halle-Wittenberg - von-Seckendorff-Platz 1, 06099 Halle, Germany, EU
2 Laboratory for Gait & Neurodynamics, Movement Disorders Unit, Department of Neurology, Tel Aviv Sourasky Medical Center - 6 Weizmann Street, Tel Aviv 64239, Israel
3 Schlafmedizinisches Zentrum der Charité Berlin - Luisenstraße 13a, 10117 Berlin, Germany, EU
4 Department of Physical Therapy, Tel Aviv University - Ramat Aviv, Israel
Corresponding author: email@example.com
Accepted: 28 January 2010
We study the effects of Parkinson's disease (PD) on phase synchronisation and cross-modulation of instantaneous amplitudes and frequencies for brain waves during sleep. Analysing data from 40 full-night EEGs (electro-encephalograms) of ten patients with PD and ten age-matched healthy controls we find that phase synchronisation between the left and right hemisphere of the brain is characteristically reduced in patients with PD. Since there is no such difference in phase synchronisation for EEGs from the same hemisphere, our results suggest the possibility of a relation with problems in coordinated motion of left and right limbs in some patients with PD. Using the novel technique of amplitude and frequency cross-modulation analysis, relating oscillations in different EEG bands and distinguishing both positive and negative modulation, we observe an even more significant decrease in patients for several band combinations.
PACS: 89.75.-k – Complex systems / 87.19.le – EEG and MEG / 87.19.lm – Synchronization in the nervous system
© EPLA, 2010
Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.
Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.
Initial download of the metrics may take a while.