| Issue |
EPL
Volume 97, Number 6, March 2012
|
|
|---|---|---|
| Article Number | 66002 | |
| Number of page(s) | 6 | |
| Section | Condensed Matter: Structural, Mechanical and Thermal Properties | |
| DOI | https://doi.org/10.1209/0295-5075/97/66002 | |
| Published online | 13 March 2012 | |
Synthetic reverberating activity patterns embedded in networks of cortical neurons
1
Gonda Interdisciplinary Brain Research Center, and the Goodman Faculty of Life Sciences, Bar-Ilan University Ramat-Gan 52900, Israel
2
Network Biology Research Laboratories, Technion, Israel Institute of Technology - Haifa 32000, Israel
3
Department of Physics, Bar-Ilan University - Ramat-Gan 52900, Israel
Received:
2
January
2012
Accepted:
13
February
2012
Synthetic reverberating activity patterns are experimentally generated by stimulation of a subset of neurons embedded in a spontaneously active network of cortical cells in vitro. The neurons are artificially connected by means of a conditional stimulation matrix, forming a synthetic local circuit with a predefined programmable connectivity and time delays. Possible uses of this experimental design are demonstrated, analyzing the sensitivity of these deterministic activity patterns to transmission delays and to the nature of ongoing network dynamics.
PACS: 64.60.aq – Networks / 02.10.Ox – Combinatorics; graph theory / 87.18.Sn – Neural networks and synaptic communication
© EPLA, 2012
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